BDBM50155773 CHEMBL3781751::US9469597, 5

SMILES [H][C@@]1(CC[C@H](N)CC1)N[C@@H]1C[C@H]1c1ccccc1

InChI Key InChIKey=ALHBJBCQLJZYON-ZQDZILKHSA-N

Data  4 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50155773   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant LSD1 using H3K4me2 as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)
Affinity DataIC50:  11nMAssay Description:Inhibition of full length LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE) using H3K4me2 peptide as substrate after 30 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)
Affinity DataIC50:  18nMAssay Description:Inhibition of human LSD1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50155773(CHEMBL3781751 | US9469597, 5)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptide as substrate incubated for 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails PubMed